848644-86-0
Chemical Structure
HSDVHK-NH2
- CAS No.: 848644-86-0
- Formula:C30H48N12O9
- Molecular Weight:720.78
IUPAC Name: (S)-3-((S)-2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-3-hydroxypropanamido)-4-(((S)-1-(((S)-1-(((S)-1,6-diamino-1-oxohexan-2-yl)amino)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid
InChIKey: FSVRGWKWZIRBPC-KESUXUJOSA-N
SMILES: NCCCC[C@@H](C(N)=O)NC([C@H](CC1=CNC=N1)NC([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H](CC2=CNC=N2)N)=O)=O)=O)=O)=O
Biological Activity:
HSDVHK-NH2 is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC50 of 1.74 pg/mL (2.414 pM)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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HSDVHK-NH2 | 99.54% | HSDVHK-NH2 is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC50 of 1.74 pg/mL (2.414 pM). |
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Similarity Score 0.71
HY-P0235CDK2 -
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HY-P11154HAV peptide -
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HY-P1829Angiotensin I/II (1-6) -
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HY-P0216A 779 -
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HY-P1758IFN-α Receptor Recognition Peptide 1 -
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HY-P11089TP53 neoepitope -
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HY-P0284C-telopeptide -
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HY-P1750Shepherdin (79-87) -
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References
- [1]. Yoonsuk Lee, et al. High-throughput screening of novel peptide inhibitors of an integrin receptor from the hexapeptide library by using a protein microarray chip. J Biomol Screen. 2004 Dec;9(8):687-94. [Content Brief]
- [2]. Youngjin Choi, et al. Site-specific inhibition of integrin alpha v beta 3-vitronectin association by a ser-asp-val sequence through an Arg-Gly-Asp-binding site of the integrin. Proteomics. 2010 Jan;10(1):72-80. [Content Brief]
