850180-76-6
Chemical Structure
N3-C2-NHS ester
- CAS No.: 850180-76-6
- Formula:C7H8N4O4
- Molecular Weight:212.16
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 3-azidopropanoate
InChIKey: WATICTZQAVLEKN-UHFFFAOYSA-N
SMILES: O=C(ON1C(CCC1=O)=O)CCN=[N+]=[N-]
Biological Activity: N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N3-C2-NHS ester | 99.77% | N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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Similarity Score 0.92
HY-140755Aeide-C1-NHS ester -
Similarity Score 0.84
HY-1361593-Mercaptopropionic acid NHS ester -
Similarity Score 0.83
HY-114512m-PEG1-NHS ester -
Similarity Score 0.82
HY-126511Propargyl-C1-NHS ester -
Similarity Score 0.81
HY-126512Propargyl-C2-NHS ester -
Similarity Score 0.80
HY-W012166N-Succinimidyl bromoacetate -
Similarity Score 0.80
HY-W011541SIA Crosslinker -
Similarity Score 0.79
HY-I01962,5-Dioxopyrrolidin-1-yl 2-cyanoacetate -
Similarity Score 0.79
HY-W4514602,5-Dioxopyrrolidin-1-yl 2-(prop-2-yn-1-yloxy)acetate -
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