853995-60-5
Chemical Structure
GNQWFI
- CAS No.: 853995-60-5
- Formula:C37H49N9O9
- Molecular Weight:763.84
InChIKey: UFZMZOJSSRKSIZ-HQNBLUNESA-N
SMILES: CC[C@H](C)[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CC(N)=O)NC(CN)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O
Biological Activity: GNQWFI, an anti-Flt1 peptide, is a VEGFR1-specific antagonist. GNQWFI blocks the interaction of VEGFR1 with various VEGFR1 ligands, such as VEGFA, VEGFB, and placental growth factor (PIGF) and inhibits VEGF-induced endothelial cell migration and tube formation. GNQWFI is promising for research of cancer, asthma, and other ocular diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GNQWFI | 99.45% | GNQWFI, an anti-Flt1 peptide, is a VEGFR1-specific antagonist. GNQWFI blocks the interaction of VEGFR1 with various VEGFR1 ligands, such as VEGFA, VEGFB, and placental growth factor (PIGF) and inhibits VEGF-induced endothelial cell migration and tube formation. GNQWFI is promising for research of cancer, asthma, and other ocular diseases. | ||||||||||||||||||||
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Keywords
