855-97-0
855-97-0
Chemical Structure
5,7,3',4'-Tetramethoxyflavone
- CAS No.: 855-97-0
- Formula:C19H18O6
- Molecular Weight:342.35
IUPAC Name: 2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one
InChIKey: CLXVBVLQKLQNRQ-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=C1C(OC)=CC(OC)=C3
Biological Activity: 5,7,3',4'-Tetramethoxyflavone, an orally active polymethoxyflavones (PMFs) that can be isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5,7,3',4'-Tetramethoxyflavone | 98.50% | 5,7,3',4'-Tetramethoxyflavone, an orally active polymethoxyflavones (PMFs) that can be isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling. | ||||||||||||||||||||
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Recoflavone (Standard) | ≥98% | Recoflavone (Standard) is the analytical standard of Recoflavone (HY-106449). This product is intended for research and analytical applications. Recoflavone (DA-6034 (free acid)), a synthetic derivative of the flavonoid Eupatilin (HY-N0783), is orally active. Recoflavone can inhibit the NF-κB pathway and induce [Ca(2+)]i increase in epithelial cells. Recoflavone exhibits activities such as anti-inflammation, anti-tumor effects, protection of gastric and intestinal mucosa, and promotion of secretion in the ocular surface and salivary glands. Recoflavone can be used for the research of diseases such as dry eye, gastric injury, and intestinal injury. | ||||||||||||||||||||
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5,7-Dimethoxyluteolin | 99.54% | 5,7-Dimethoxyluteolin, a 5,7-dimethylluteolin derivative, is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM. | ||||||||||||||||||||
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4'-Methylchrysoeriol | 99.17% | 4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD. | ||||||||||||||||||||
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Sinensetin | 99.66% | Sinensetin is a methylated flavonoid found in fruits that has strong anti-vascular and anti-inflammatory properties. | ||||||||||||||||||||
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5,7,4'-Trimethoxyflavone | 99.21% | 5,7,4’-Trimethoxyflavone can be isolated from the medicinal plant Kaempferia parviflora (KP). 5,7,4’-Trimethoxyflavone is a CFTR activator and EC50 is 64 μM. 5,7,4’-Trimethoxyflavone induces apoptosis, increases proteolytic activation of caspase-3, and degradation of ADP-ribose polymerase (PARP) protein. 5,7,4’-Trimethoxyflavone has antitumor activity. 5,7,4’-Trimethoxyflavone can be used to prevent skin aging and oxidative stress. | ||||||||||||||||||||
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7,3',4'-Tri-O-methylluteolin | 99.20% | 7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) is a flavonoid with multiple biological activities. 7,3',4'-Tri-O-methylluteolin inhibits soybean lipoxygenase (LOX), with an IC50 value of 23.97 µg/mL. 7,3',4'-Tri-O-methylluteolin possesses anti-inflammatory effects in Lipopolysaccharides (HY-D1056) (LPS)-induced RAW 264.7 macrophages. 7,3',4'-Tri-O-methylluteolin inhibits the binding of MDM2 with p53 and induces apoptosis in MCF-7 breast cancer cells. 7,3',4'-Tri-O-methylluteolin also has antioxidant, antifungal and antitrypanosomal activities. | ||||||||||||||||||||
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3',4',5',5,7-Pentamethoxyflavone | 99.45% | 3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic agents by inhibition of Nrf2 pathway. | ||||||||||||||||||||
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Corymbosin | Corymbosin is a glucoside. Corymbosin can be isolated from the aerial parts of Ballota glandulosissima. Corymbosin also has antifungal flavonoid activity. | |||||||||||||||||||||
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5-Desmethylsinensetin | 99.06% | 5-desmethylsinensetin, isolated from Artemisia princeps , possesses antiprotozoal activity. 5-desmethylsinensetin shows IC50 values of 0.4 μg/mL on T. cruzi epimastigotes and 75.1 μg/mL on trypomastigotes, respectively. | ||||||||||||||||||||
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Averionol | Averionol (Compound 26) is a flavonoid compound. Averionol has no significant inhibitory activity against HIV integrase. Averionol can be used in the development of anti-HIV agents. | |||||||||||||||||||||
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