857064-42-7
857064-42-7
Chemical Structure
WP-1034
- CAS No.: 857064-42-7
- Formula:C18H15N3O3
- Molecular Weight:321.33
IUPAC Name: (R,E)-2-cyano-3-(4-nitrophenyl)-N-(1-phenylethyl)acrylamide
InChIKey: RYYNDHCHTCVQJH-KWWJGWKXSA-N
SMILES: O=C(N[C@@H](C1=CC=CC=C1)C)/C(C#N)=C/C2=CC=C([N+]([O-])=O)C=C2
Biological Activity: WP-1034 is a JAK-STAT inhibitor with proapoptotic and antileukemic activity in acute myeloid leukemia (AML). WP-1034 blocks activation of Stat 3 and 5. WP-1034 induces cell cycle arrest and triggers apoptosis. WP-1034 can be used for AML research[1].
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WP-1034 | WP-1034 is a JAK-STAT inhibitor with proapoptotic and antileukemic activity in acute myeloid leukemia (AML). WP-1034 blocks activation of Stat 3 and 5. WP-1034 induces cell cycle arrest and triggers apoptosis. WP-1034 can be used for AML research. | |||||||||||||||||||||
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References
Keywords
