86-86-2
Chemical Structure
1-Naphthylacetamide
Synonym(s): NAAM; 1-Naphthaleneacetamide; α-Naphthylacetamide
- CAS. Nr.: 86-86-2
- Formula:C12H11NO
- Molecular Weight:185.23
IUPAC Name: 2-(naphthalen-1-yl)acetamide
InChIKey: XFNJVKMNNVCYEK-UHFFFAOYSA-N
SMILES: O=C(N)CC1=CC=CC=2C=CC=CC21
Biological Activity: 1-Naphthylacetamide is an orally active nonsteroidal anti-inflammatory agent (NAIA) and also an indole-type auxin plant growth regulator. 1-Naphthylacetamide inhibits inflammatory response-related pathways and modulates plant hormone signaling, exhibiting anti-inflammatory, local anesthetic, antispasmodic, analgesic, and diuretic activities. 1-Naphthylacetamide promotes plant cell expansion, differentiation, and fruit enlargement. Additionally, 1-Naphthylacetamide induces central nervous system (CNS) depression in mice, characterized by reduced spontaneous activity, decreased irritability, decreased muscle tone, and attenuated ear-cuff reflex, ipsilateral flexor reflex, and corneal reflex[1][2].
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1-Naphthylacetamide | 1-Naphthylacetamide is an orally active nonsteroidal anti-inflammatory agent (NAIA) and also an indole-type auxin plant growth regulator. 1-Naphthylacetamide inhibits inflammatory response-related pathways and modulates plant hormone signaling, exhibiting anti-inflammatory, local anesthetic, antispasmodic, analgesic, and diuretic activities. 1-Naphthylacetamide promotes plant cell expansion, differentiation, and fruit enlargement. Additionally, 1-Naphthylacetamide induces central nervous system (CNS) depression in mice, characterized by reduced spontaneous activity, decreased irritability, decreased muscle tone, and attenuated ear-cuff reflex, ipsilateral flexor reflex, and corneal reflex. | |||||||||||||||||||||
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