862909-67-9
862909-67-9
Chemical Structure
Epiboxidine hydrochloride
- CAS No.: 862909-67-9
- Formula:C10H15ClN2O
- Molecular Weight:214.69
IUPAC Name: 5-((1R,2S,4S)-7-azabicyclo[2.2.1]heptan-2-yl)-3-methylisoxazole hydrochloride
InChIKey: NSMIYECGCNTSSS-CTERPIQNSA-N
SMILES: CC1=NOC([C@@H]2[C@@H]3N[C@@H](CC3)C2)=C1.[H]Cl
Biological Activity: Epiboxidine hydrochloride is a potent and selective neural nAChR agonist with Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. Epiboxidine hydrochloride is a methylisoxazole analog of the alkaloid Epibatidine, and is also an analog of another nAChR agonist, ABT 418[1].
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Epiboxidine hydrochloride | Epiboxidine hydrochloride is a potent and selective neural nAChR agonist with Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. Epiboxidine hydrochloride is a methylisoxazole analog of the alkaloid Epibatidine, and is also an analog of another nAChR agonist, ABT 418. | |||||||||||||||||||||
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References
Keywords
