86347-14-0
86347-14-0
Chemical Structure
Medetomidine
- CAS No.: 86347-14-0
- Formula:C13H16N2
- Molecular Weight:200.28
IUPAC Name: 5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole
InChIKey: CUHVIMMYOGQXCV-UHFFFAOYSA-N
SMILES: CC(C1=CN=CN1)C2=CC=CC(C)=C2C
Biological Activity: Medetomidine is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine has sedative and analgesic effects. Medetomidine can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Medetomidine | 99.75% | Medetomidine is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine has sedative and analgesic effects. Medetomidine can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. | ||||||||||||||||||||
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Medetomidine (Standard) | ≥98% | Medetomidine (Standard) is the analytical standard of Medetomidine. This product is intended for research and analytical applications. Medetomidine is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine has sedative and analgesic effects. Medetomidine can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. | ||||||||||||||||||||
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Medetomidine-d5 (d5-Major) | Medetomidine-d5 (d5-Major) is the deuterium labeled Medetomidine (HY-17034). Medetomidine is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine has sedative and analgesic effects. Medetomidine can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. | |||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Kallio A, et al. Acute effects of medetomidine, a selective alpha 2-adrenoceptor agonist, on anterior pituitary hormone and cortisol secretion in man. Acta Endocrinol (Copenh). 1988 Sep;119(1):11-5. [Content Brief]
- [3]. R Virtanen, et al. Characterization of the selectivity, specificity and potency of medetomidine as an a2-adrenoceptor agonist. [Content Brief]
- [4]. O. B. Ansah, et al. Comparing oral and intramuscular administration of medetomidine in cats.
