2. Metabolic Enzyme/Protease Neuronal Signaling Immunology/Inflammation GPCR/G Protein
  3. Cytochrome P450 Histamine Receptor
  4. FUB 349

FUB 349 (Compound 8) is a selective Aromatase inhibitor with an IC50 of 12  μM. FUB 349 is also a H3 receptor antagonist with Kis of 12 and 2.1 nM for rH3R and hH3R, respectively. FUB 349 can be used for neurological diseases such as cognitive impairment research.

For research use only. We do not sell to patients.

FUB 349

FUB 349 Chemical Structure

CAS No. : 184023-52-7

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FUB 349 Related Antibodies

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CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A CYP3A4 CYP17A1

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Description

FUB 349 (Compound 8) is a selective Aromatase inhibitor with an IC50 of 12  μM. FUB 349 is also a H3 receptor antagonist with Kis of 12 and 2.1 nM for rH3R and hH3R, respectively. FUB 349 can be used for neurological diseases such as cognitive impairment research[1][2].

IC50 & Target[2]

Aromatase

50 μM (IC50)

human H3 receptor

2.1 nM (Ki)

rat H3 receptor

12 nM (Ki)

Molecular Weight

200.28

Formula

C13H16N2
CAS No.
SMILES

C1(CCCCC2=CC=CC=C2)=CN=CN1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FUB 349 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FUB 349184023-52-7FUB349FUB-349Cytochrome P450Histamine ReceptorCYPsAromataseH3 receptorneurological diseasesInhibitorinhibitorinhibit

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