864431-36-7
Chemical Structure
SBI-0087702
- CAS No.: 864431-36-7
- Formula:C21H23NO2
- Molecular Weight:321.41
IUPAC Name: N-((4-methoxynaphthalen-1-yl)methyl)-2-(4-methoxyphenyl)ethan-1-amine
InChIKey: SNBZXHDTILHVJS-UHFFFAOYSA-N
SMILES: COC1=CC=C(CCNCC2=C3C=CC=CC3=C(OC)C=C2)C=C1
Biological Activity: SBI-0087702 promots the cytoplasmic localization of ATF2 in melanoma cells. SBI-0087702-induced translocation of ATF2 to the mitochondria results in increased apoptosis due to loss of mitochondrial membrane integrity. SBI-0087702 also inhibits growth and motility of melanoma cells. SBI-0087702 was shown to inhibit ATF2 phosphorylation on Thr52 by PKCε[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SBI-0087702 | 99.55% | SBI-0087702 promots the cytoplasmic localization of ATF2 in melanoma cells. SBI-0087702-induced translocation of ATF2 to the mitochondria results in increased apoptosis due to loss of mitochondrial membrane integrity. SBI-0087702 also inhibits growth and motility of melanoma cells. SBI-0087702 was shown to inhibit ATF2 phosphorylation on Thr52 by PKCε. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.78
HY-100230AML133 hydrochloride -
Similarity Score 0.77
HY-100230ML-133 -
Similarity Score 0.71
HY-17068325H-NB4OMe hydrochloride -
Similarity Score 0.70
HY-N12157Noratherosperminine -
Similarity Score 0.70
HY-W72215525H-NBOH hydrochloride -
Similarity Score 0.69
HY-N12157ANoratherosperminine hydrochloride -
Similarity Score 0.69
HY-W275220PEA-NBOMe hydrochloride -
Similarity Score 0.69
HY-13035125H-NBOMe hydrochloride -
Similarity Score 0.68
HY-N7648Atherosperminine -
Explore the MedChemAI to find more analogs
