874-14-6
874-14-6
Chemical Structure
1,3-Dimethyluracil
- CAS No.: 874-14-6
- Formula:C6H8N2O2
- Molecular Weight:140.14
IUPAC Name: 1,3-dimethylpyrimidine-2,4(1H,3H)-dione
InChIKey: JSDBKAHWADVXFU-UHFFFAOYSA-N
SMILES: CN1C=CC(=O)N(C)C1=O
Biological Activity: 1,3-Dimethyluracil is a pyrimidone derives from a uracil. 1,3-Dimethyluracil found occasionally in human urine. 1,3-Dimethyluracil shows inhibition activity against hCA I and hCA II (human carbonic anhydrase) with Ki of 316.2 μM and 166.4 μM, respectively[1][2].
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1,3-Dimethyluracil | 99.98% | 1,3-Dimethyluracil is a pyrimidone derives from a uracil. 1,3-Dimethyluracil found occasionally in human urine. 1,3-Dimethyluracil shows inhibition activity against hCA I and hCA II (human carbonic anhydrase) with Ki of 316.2 μM and 166.4 μM, respectively. | ||||||||||||||||||||
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1,3-Dimethyluracil (Standard) | ≥98% | 1,3-Dimethyluracil is a pyrimidone derives from a uracil. 1,3-Dimethyluracil found occasionally in human urine. 1,3-Dimethyluracil shows inhibition activity against hCA I and hCA II (human carbonic anhydrase) with Ki of 316.2 μM and 166.4 μM, respectively. | ||||||||||||||||||||
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References
- [1]. Stoessel D, et al. Promising Metabolite Profiles in the Plasma and CSF of Early Clinical Parkinson's Disease. Front Aging Neurosci. 2018 Mar 5;10:51. [Content Brief]
- [2]. Güney M, et al. Synthesis and carbonic anhydrase inhibitory properties of novel uracil derivatives. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3261-3. [Content Brief]
