874-14-6
874-14-6
Chemical Structure
1,3-Dimethyluracil
- CAS No.: 874-14-6
- Formula:C6H8N2O2
- Molecular Weight:140.14
IUPAC Name: 1,3-dimethylpyrimidine-2,4(1H,3H)-dione
InChIKey: JSDBKAHWADVXFU-UHFFFAOYSA-N
SMILES: CN1C=CC(=O)N(C)C1=O
Biological Activity: 1,3-Dimethyluracil is a pyridine derivative of Uracil (HY-I0960). 1,3-Dimethyluracil is occasionally found in human urine. 1,3-Dimethyluracil exhibits inhibitory activity against hCA I and hCA II, with Ki values of 316.2 μM and 166.4 μM, respectively. 1,3-Dimethyluracil can be used for Parkinson's disease research[1][2].
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1,3-Dimethyluracil | 99.98% | 1,3-Dimethyluracil is a pyridine derivative of Uracil (HY-I0960). 1,3-Dimethyluracil is occasionally found in human urine. 1,3-Dimethyluracil exhibits inhibitory activity against hCA I and hCA II, with Ki values of 316.2 μM and 166.4 μM, respectively. 1,3-Dimethyluracil can be used for Parkinson's disease research. | ||||||||||||||||||||
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1,3-Dimethyluracil (Standard) | ≥98% | 1,3-Dimethyluracil (Standard) is the analytical standard of 1,3-Dimethyluracil (HY-W008343). This product is intended for research and analytical applications. 1,3-Dimethyluracil is a pyridine derivative of Uracil (HY-I0960). 1,3-Dimethyluracil is occasionally found in human urine. 1,3-Dimethyluracil exhibits inhibitory activity against hCA I and hCA II, with Ki values of 316.2 μM and 166.4 μM, respectively. 1,3-Dimethyluracil can be used for Parkinson's disease research. | ||||||||||||||||||||
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References
- [1]. Stoessel D, et al. Promising Metabolite Profiles in the Plasma and CSF of Early Clinical Parkinson's Disease. Frontiers in aging neuroscience. 2018;10:51. [Content Brief]
- [2]. Güney M, et al. Synthesis and carbonic anhydrase inhibitory properties of novel uracil derivatives. Bioorganic & medicinal chemistry letters. 2015 Aug 15;25(16):3261-3. [Content Brief]
