874484-20-5
874484-20-5
Chemical Structure
S29434
Synonym(s): NMDPEF
- CAS No.: 874484-20-5
- Formula:C21H18N4O3
- Molecular Weight:374.39
IUPAC Name: N-(2-(2-methoxy-6H-dipyrido[2,3-a:3',2'-e]pyrrolizin-11-yl)ethyl)furan-2-carboxamide
InChIKey: XJIUMLVQBQKCJA-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CO1)NCCC2=C(C3=NC=CC=C3C4)N4C5=CC=C(OC)N=C52
Biological Activity: S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 induces autophagy and inhibits QR2-mediated ROS production[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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S29434 | 99.29% | S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 induces autophagy and inhibits QR2-mediated ROS production. | ||||||||||||||||||||
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