882268-69-1
882268-69-1
Chemical Structure
HIF-2α-IN-4
- CAS 番号: 882268-69-1
- Formula:C9H9N3O4S2
- Molecular Weight:287.32
IUPAC Name: methyl (E)-3-(2-(cyano(methylsulfonyl)methylene)hydrazinyl)thiophene-2-carboxylate
InChIKey: OOGAPDPPVHJYGJ-KPKJPENVSA-N
SMILES: O=C(C1=C(N/N=C(C#N)/S(=O)(C)=O)C=CS1)OC
Biological Activity: HIF-2α-IN-4 is a potent inhibitor of hypoxia inducible factor-2α (HIF-2α) translation, with an IC50 of 5 μM. HIF-2α-IN-4 decreases both constitutive and hypoxia-induced HIF-2α protein expression. HIF-2α-IN-4 links its 5'UTR iron-responsive element to oxygen sensing[1].
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HIF-2α-IN-4 | 99.96% | HIF-2α-IN-4 is a potent inhibitor of hypoxia inducible factor-2α (HIF-2α) translation, with an IC50 of 5 μM. HIF-2α-IN-4 decreases both constitutive and hypoxia-induced HIF-2α protein expression. HIF-2α-IN-4 links its 5'UTR iron-responsive element to oxygen sensing. | ||||||||||||||||||||
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References
Keywords
