889959-22-2
889959-22-2
Chemical Structure
CYP19A1-IN-1
- CAS No.: 889959-22-2
- Formula:C21H16ClN3O3
- Molecular Weight:393.82
InChIKey: JHLPBFOWDHHRBC-UHFFFAOYSA-N
SMILES: CC(C1=CC=C(C=C1)N2C=CN=C2)NC(C3=CC4=CC(Cl)=CC=C4OC3=O)=O
Biological Activity: CYP19A1-IN-1 (Compound 9) is a CYP19A1 inhibitor with an IC50 of 271 nM. CYP19A1-IN-1 inhibits the activity of converting androgens to estrogens by binding to CYP19A1. CYP19A1-IN-1 can be used in the research of sex hormone-related diseases such as estrogen-dependent breast cancer[1].
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CYP19A1-IN-1 | CYP19A1-IN-1 (Compound 9) is a CYP19A1 inhibitor with an IC50 of 271 nM. CYP19A1-IN-1 inhibits the activity of converting androgens to estrogens by binding to CYP19A1. CYP19A1-IN-1 can be used in the research of sex hormone-related diseases such as estrogen-dependent breast cancer. | |||||||||||||||||||||
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References
Keywords
