89-38-3
89-38-3
Chemical Structure
Pteropterin
Synonym(s): Pteroyltriglutamic
- CAS No.: 89-38-3
- Formula:C29H33N9O12
- Molecular Weight:699.63
IUPAC Name: ((S)-4-((S)-4-(4-(((2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl)amino)benzamido)-4-carboxybutanamido)-4-carboxybutanoyl)-L-glutamic acid
InChIKey: WOLQREOUPKZMEX-BZSNNMDCSA-N
SMILES: O=C(CC[C@H](NC(CC[C@H](NC(CC[C@H](NC(C1=CC=C(C=C1)NCC2=CN=C3NC(N)=NC(C3=N2)=O)=O)C(O)=O)=O)C(O)=O)=O)C(O)=O)O
Biological Activity: Pteropterin (Pteroyltriglutamic) is an active form of folate. Pteropterin shows inhibiting effect on tumor growth and has broad anticancer activity[1][2].
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Pteropterin | Pteropterin (Pteroyltriglutamic) is an active form of folate. Pteropterin shows inhibiting effect on tumor growth and has broad anticancer activity. | |||||||||||||||||||||
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References
- [1]. Stine ZE, et al. Targeting cancer metabolism in the era of precision oncology. Nat Rev Drug Discov. 2022 Feb;21(2):141-162. [Content Brief]
- [2]. Muthu M, et al. Current Status and Future Prospects of Clinically Exploiting Cancer-specific Metabolism-Why Is Tumor Metabolism Not More Extensively Translated into Clinical Targets and Biomarkers? Int J Mol Sci. 2019 Mar 19;20(6):1385. [Content Brief]
Keywords
