896657-58-2
Chemical Structure
MGH-CP1
- CAS No.: 896657-58-2
- Formula:C20H24N4OS
- Molecular Weight:368.50
IUPAC Name: 2-((4H-1,2,4-triazol-3-yl)thio)-N-(4-((3r,5r,7r)-adamantan-1-yl)phenyl)acetamide
InChIKey: UUKXOVBCMOZQNC-XLWGHNRJSA-N
SMILES: O=C(CSC1=NN=CN1)NC2=CC=C(C=C2)C3(C[C@H](C4)C5)C[C@H]5C[C@H]4C3
Biological Activity: MGH-CP1 is a potent and orally active TEAD2 and TEAD4 auto-palmitoylation inhibitor with IC50s of 710 nM and 672 nM, respectively. MGH-CP1 can decrease the palmitoylation levels of endogenous or ectopically expressed TEAD proteins in cells. MGH-CP1 can suppress Myc expression, inhibit epithelial over-proliferation, and induce apoptosis when together with Lats1/2 deletion[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MGH-CP1 | 99.56% | MGH-CP1 is a potent and orally active TEAD2 and TEAD4 auto-palmitoylation inhibitor with IC50s of 710 nM and 672 nM, respectively. MGH-CP1 can decrease the palmitoylation levels of endogenous or ectopically expressed TEAD proteins in cells. MGH-CP1 can suppress Myc expression, inhibit epithelial over-proliferation, and induce apoptosis when together with Lats1/2 deletion. | ||||||||||||||||||||
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Similarity Score 0.53
HY-W10499045-(Adamantan-1-yl)isophthalic acid -
Similarity Score 0.50
HY-Z7812RAdapalene impurity 1 (Standard) -
Similarity Score 0.48
HY-144426Neuraminidase-IN-6 -
Similarity Score 0.46
HY-101145CK37 -
Similarity Score 0.46
HY-172519LSD1-IN-41 -
Similarity Score 0.46
HY-W1123964,4',4''-((1S,3S,5S)-Adamantane-1,3,5-triyl)tribenzoic acid -
Similarity Score 0.45
HY-110122AZ 12216052 -
Similarity Score 0.45
HY-121095ABizine dihydrochloride -
Similarity Score 0.45
HY-114804BRD2577 -
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