CK37
CK37 is a competitive choline kinase-α inhibitor. CK37 inhibits purified recombinant human choline kinase-α activity. CK37 suppresses MAPK and PI3K/AKT signaling, disrupts actin cytoskeletal organization. CK37 diminishs activating phosphorylations of ERK. CK37 exhibits anticancer activity against cervical cancer, melanoma, Lewis lung carcinoma, lung adenocarcinoma, breast cancer, and leukemia.
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- CAS No.: 1001478-90-5
- Formule: C20H22N4OS
- Masse moléculaire:366.48
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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CHKα1 |
CHKα2 |
Chemical Information
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CAS No. 1001478-90-5
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Masse moléculaire 366.48
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Formule C20H22N4OS
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SMILES
O=C(NC1=CC(C)=CC(C)=C1)CSC2=NN=C(C3=CC=C(CC)C=C3)N2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)