CK37
CK37 is a competitive choline kinase-α inhibitor. CK37 inhibits purified recombinant human choline kinase-α activity. CK37 suppresses MAPK and PI3K/AKT signaling, disrupts actin cytoskeletal organization. CK37 diminishs activating phosphorylations of ERK. CK37 exhibits anticancer activity against cervical cancer, melanoma, Lewis lung carcinoma, lung adenocarcinoma, breast cancer, and leukemia.
For research use only. We do not sell to patients.
- CAS No.: 1001478-90-5
- Formula: C20H22N4OS
- Molecular Weight:366.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CHKα1 |
CHKα2 |
Chemical Information
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CAS No. 1001478-90-5
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Molecular Weight 366.48
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Formula C20H22N4OS
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SMILES
O=C(NC1=CC(C)=CC(C)=C1)CSC2=NN=C(C3=CC=C(CC)C=C3)N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)