91-80-5
91-80-5
Chemical Structure
Methapyrilene
- CAS No.: 91-80-5
- Formula:C14H19N3S
- Molecular Weight:261.39
IUPAC Name: N1,N1-dimethyl-N2-(pyridin-2-yl)-N2-(thiophen-2-ylmethyl)ethane-1,2-diamine
InChIKey: HNJJXZKZRAWDPF-UHFFFAOYSA-N
SMILES: CN(C)CCN(C1=NC=CC=C1)CC2=CC=CS2
Biological Activity:
Methapyrilene is a histamine antagonist, a pyridine chemical with anticholinergic activity. Methapyrilene can cause target organ-specific epigenetic alterations, such as a decrease in DNA methylation levels. Methapyrilene induces hepatocellular carcinoma in rats[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Methapyrilene | 99.66% | Methapyrilene is a histamine antagonist, a pyridine chemical with anticholinergic activity. Methapyrilene can cause target organ-specific epigenetic alterations, such as a decrease in DNA methylation levels. Methapyrilene induces hepatocellular carcinoma in rats. |
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References
- [1]. Volodymyr Tryndyak, et al. Effect of aflatoxin B1, benzo[a]pyrene, and methapyrilene on transcriptomic and epigenetic alterations in human liver HepaRG cells. Food Chem Toxicol. 2018 Nov;121:214-223. [Content Brief]
- [2]. Andrew Craig, et al. Systems toxicology: integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat. J Proteome Res. 2006 Jul;5(7):1586-60 [Content Brief]
Keywords
