Methapyrilene (Standard)
Methapyrilene (Standard) is the analytical standard of Methapyrilene (HY-111130). This product is intended for research and analytical applications. Methapyrilene is a histamine antagonist, a pyridine chemical with anticholinergic activity. Methapyrilene can cause target organ-specific epigenetic alterations, such as a decrease in DNA methylation levels. Methapyrilene induces hepatocellular carcinoma in rats.
For research use only. We do not sell to patients.
- CAS No.: 91-80-5
- Formula: C14H19N3S
- Molecular Weight:261.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 91-80-5
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Molecular Weight 261.39
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Formula C14H19N3S
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SMILES
CN(C)CCN(C1=NC=CC=C1)CC2=CC=CS2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Volodymyr Tryndyak, et al. Effect of aflatoxin B1, benzo[a]pyrene, and methapyrilene on transcriptomic and epigenetic alterations in human liver HepaRG cells. Food Chem Toxicol. 2018 Nov;121:214-223. [Content Brief]
[2]. Andrew Craig, et al. Systems toxicology: integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat. J Proteome Res. 2006 Jul;5(7):1586-60 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)