915082-52-9
915082-52-9
Chemical Structure
PDE4B-IN-2
- CAS No.: 915082-52-9
- Formula:C19H18ClN3O2S
- Molecular Weight:387.88
IUPAC Name: 2-(4-((2-(5-chlorothiophen-2-yl)-5-ethyl-6-methylpyrimidin-4-yl)amino)phenyl)acetic acid
InChIKey: FDVSPBLZPJMXFV-UHFFFAOYSA-N
SMILES: O=C(O)CC1=CC=C(NC2=NC(C3=CC=C(Cl)S3)=NC(C)=C2CC)C=C1
Biological Activity: PDE4B-IN-2 is an orally active and selective PDE4B inhibitor with an IC50 of 15 nM. PDE4B-IN-2 inhibits PDE4D (IC50=1.7 μM). PDE4B-IN-2 exhibits potent anti-inflammatory effects[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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PDE4B-IN-2 | 99.59% | PDE4B-IN-2 is an orally active and selective PDE4B inhibitor with an IC50 of 15 nM. PDE4B-IN-2 inhibits PDE4D (IC50=1.7 μM). PDE4B-IN-2 exhibits potent anti-inflammatory effects. | ||||||||||||||||||||
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Structural Analogs
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HY-119612XCT0135908 -
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HY-137466ARN-21934 -
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HY-138967BRF110 -
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HY-117571Zatolmilast -
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HY-108594PD-118057 -
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HY-164455AJI-214 -
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HY-178712CT 32228 -
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