920868-45-7
Chemical Structure
MASM7
- CAS 番号: 920868-45-7
- Formula:C22H23N5O2S2
- Molecular Weight:453.58
IUPAC Name: 2-(2-((5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)propanamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
InChIKey: MTAWXPCGCQTSOJ-UHFFFAOYSA-N
SMILES: O=C(N)C1=C(SC2=C1CCC2)NC(C(C)SC3=NN=C(C4CC4)N3C5=CC=CC=C5)=O
Biological Activity: MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins. MASM7 can increase Mito AR with an EC50 value of 75 nM in MEFs in concentration-responsively, and can promote mitochondrial fusion by directly activating MFN2 or MFN. MASM7 also demonstrates direct binding to the HR2 domain of MFN2 with Kd value of 1.1 μM[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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MASM7 | 99.85% | MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins. MASM7 can increase Mito AR with an EC50 value of 75 nM in MEFs in concentration-responsively, and can promote mitochondrial fusion by directly activating MFN2 or MFN. MASM7 also demonstrates direct binding to the HR2 domain of MFN2 with Kd value of 1.1 μM. | ||||||||||||||||||||
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