936544-53-5
Chemical Structure
Palmitoyl tripeptide-8
- CAS No.: 936544-53-5
- Formula:C37H61N9O4
- Molecular Weight:695.94
InChIKey: WBHUVOTYPRYBNG-QAXCHELISA-N
SMILES: CCCCCCCCCCCCCCCC(N[C@@H](CC1=CN=CN1)C(N[C@@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)CC2=CC=CC=C2)=O)=O
Biological Activity: Palmitoyl tripeptide-8 is an immunomodulatory peptide and neurotransmitter inhibitory peptide. Palmitoyl tripeptide-8 inhibits the activation of the NF-κB pathway and the production of pro-inflammatory cytokines (IL-8, IL-6, and TNF-α). Palmitoyl tripeptide-8 activates the cutaneous opioid system and reduces CGRP release. Palmitoyl tripeptide-8 decreases the number of dilated capillaries, the size of dilated vessels, and the degree of edema in skin explants treated with Substance P (HY-P0201). Palmitoyl tripeptide-8 is used as an active ingredient in cosmetics for sensitive skin. Palmitoyl tripeptide-8 is utilized in research related to sensitive skin[1][2].
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Palmitoyl tripeptide-8 | Palmitoyl tripeptide-8 is an immunomodulatory peptide and neurotransmitter inhibitory peptide. Palmitoyl tripeptide-8 inhibits the activation of the NF-κB pathway and the production of pro-inflammatory cytokines (IL-8, IL-6, and TNF-α). Palmitoyl tripeptide-8 activates the cutaneous opioid system and reduces CGRP release. Palmitoyl tripeptide-8 decreases the number of dilated capillaries, the size of dilated vessels, and the degree of edema in skin explants treated with Substance P (HY-P0201). Palmitoyl tripeptide-8 is used as an active ingredient in cosmetics for sensitive skin. Palmitoyl tripeptide-8 is utilized in research related to sensitive skin. | |||||||||||||||||||||
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References
- [1]. Kalın İ D, et al. Reversing Time with Peptides: Mechanisms, Classifications, and Innovations in Anti-aging Interventions[J]. Commagene Journal of Biology, 10(1).
- [2]. Resende DISP, et al. Usage of Synthetic Peptides in Cosmetics for Sensitive Skin. Pharmaceuticals (Basel, Switzerland). 2021 Jul 21;14(8):702. [Content Brief]
