93738-40-0
93738-40-0
Chemical Structure
Ralitoline
- CAS No.: 93738-40-0
- Formula:C13H13ClN2O2S
- Molecular Weight:296.77
IUPAC Name: (Z)-N-(2-chloro-6-methylphenyl)-2-(3-methyl-4-oxothiazolidin-2-ylidene)acetamide
InChIKey: YJXQTIXFPYPQFT-SDQBBNPISA-N
SMILES: CC(C=CC=C1Cl)=C1NC(/C=C2N(C(CS/2)=O)C)=O
Biological Activity: Ralitoline is a sodium channel blocker with IC50 of 2 μM. Ralitoline has anticonvulsant activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ralitoline | Ralitoline is a sodium channel blocker with IC50 of 2 μM. Ralitoline has anticonvulsant activity. | |||||||||||||||||||||
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References
- [1]. Löscher W,et al. Ralitoline: a reevaluation of anticonvulsant profile and determination of "active" plasma concentrations in comparison with prototype antiepileptic drugs in mice. Epilepsia. 1991 Jul-Aug;32(4):560-8. [Content Brief]
- [2]. Rock DM, et al. Ralitoline (CI-946) and CI-953 block sustained repetitive sodium action potentials in cultured mouse spinal cord neurons and displace batrachotoxinin A 20-alpha-benzoate binding in vitro. Epilepsy Res. 1991 Apr;8(3):197-203. [Content Brief]
Keywords
