957054-33-0
957054-33-0
Chemical Structure
Pictilisib dimethanesulfonate
Synonym(s): GDC-0941 dimethanesulfonate ; GDC-0941 (2 MeSO3H salt)
- CAS No.: 957054-33-0
- Formula:C25H35N7O9S4
- Molecular Weight:705.85
IUPAC Name: 4-(2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine dimethanesulfonate
InChIKey: RFRIKACSFOTIMU-UHFFFAOYSA-N
SMILES: O=S(N1CCN(CC1)CC2=CC3=C(S2)C(N4CCOCC4)=NC(C5=CC=CC6=C5C=NN6)=N3)(C)=O.O=S(O)(C)=O.O=S(O)(C)=O
Biological Activity: Pictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pictilisib dimethanesulfonate | 99.72% | Pictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). | ||||||||||||||||||||
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Pictilisib dimethanesulfonate (Standard) | ≥98% | Pictilisib (dimethanesulfonate) (Standard) is the analytical standard of Pictilisib (dimethanesulfonate). This product is intended for research and analytical applications. Pictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). | ||||||||||||||||||||
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