987-24-6
Chemical Structure
Betamethasone acetate
- CAS No.: 987-24-6
- Formula:C24H31FO6
- Molecular Weight:434.50
IUPAC Name: 2-((8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
InChIKey: AKUJBENLRBOFTD-QZIXMDIESA-N
SMILES: C[C@@]12[C@](C[C@H](C)[C@]2(O)C(COC(C)=O)=O)([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](O)C1)=O
Biological Activity: Betamethasone acetate is a glucocorticoid with prenatal application for preventing respiratory distress syndrome (RDS) in premature infants. Betamethasone acetate exhibits dose-dependent effects on somatic and brain development in offspring when administered prenatally to pregnant rats. Betamethasone acetate can be used for the study of antenatal intervention[1][2].
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Betamethasone acetate | 99.38% | Betamethasone acetate is a glucocorticoid with prenatal application for preventing respiratory distress syndrome (RDS) in premature infants. Betamethasone acetate exhibits dose-dependent effects on somatic and brain development in offspring when administered prenatally to pregnant rats. Betamethasone acetate can be used for the study of antenatal intervention. | ||||||||||||||||||||
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Betamethasone acetate (Standard) | ≥98% | Betamethasone acetate (Standard) is the analytical standard of Betamethasone acetate (HY-13570B). This product is intended for research and analytical applications. Betamethasone acetate is a glucocorticoid with prenatal application for preventing respiratory distress syndrome (RDS) in premature infants. Betamethasone acetate exhibits dose-dependent effects on somatic and brain development in offspring when administered prenatally to pregnant rats. Betamethasone acetate can be used for the study of antenatal intervention. | ||||||||||||||||||||
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Betamethasone acetate-d5 | Betamethasone acetate-d5 is deuterium labeled Betamethasone acetate (HY-13570B). Betamethasone acetate is a glucocorticoid with prenatal application for preventing respiratory distress syndrome (RDS) in premature infants. Betamethasone acetate exhibits dose-dependent effects on somatic and brain development in offspring when administered prenatally to pregnant rats. Betamethasone acetate can be used for the study of antenatal intervention. | |||||||||||||||||||||
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References
- [1]. Schmidt AF, et al. Low-dose betamethasone-acetate for fetal lung maturation in preterm sheep. Am J Obstet Gynecol. 2018 Jan;218(1):132.e1-132.e9. [Content Brief]
- [2]. Scheepens A, et al. A single course of prenatal betamethasone in the rat alters postnatal brain cell proliferation but not apoptosis. J Physiol. 2003 Oct 1;552(Pt 1):163-75. [Content Brief]
