99129-21-2
Chemical Structure
Clethodim
- CAS No.: 99129-21-2
- Formula:C17H26ClNO3S
- Molecular Weight:359.91
IUPAC Name: 2-((Z)-1-((((E)-3-chloroallyl)oxy)imino)propyl)-5-(2-(ethylthio)propyl)-3-hydroxycyclohex-2-en-1-one
InChIKey: SILSDTWXNBZOGF-SUJSHMTESA-N
SMILES: O=C1C(/C(CC)=N\OC/C=C/Cl)=C(O)CC(CC(SCC)C)C1
Biological Activity: Clethodim is a potent acetyl-CoA A carboxylase (ACCase) inhibitor and herbicide. Clethodim inhibits ACCase in plants, thereby blocking fatty acid biosynthesis required for cell membrane and secondary metabolite production. Clethodim exhibits developmental toxicity and neurotoxicity in zebrafish embryos and larvae. Clethodim is used in studies on agricultural herbicides and developmental toxicity[1][2][3][4][5][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Clethodim | 95.0% | Clethodim is a potent acetyl-CoA A carboxylase (ACCase) inhibitor and herbicide. Clethodim inhibits ACCase in plants, thereby blocking fatty acid biosynthesis required for cell membrane and secondary metabolite production. Clethodim exhibits developmental toxicity and neurotoxicity in zebrafish embryos and larvae. Clethodim is used in studies on agricultural herbicides and developmental toxicity. | ||||||||||||||||||||
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Clethodim (Standard) | 90.71% | Clethodim Standard is the analytical standard of Clethodim (HY-119896). This product is intended for research and analytical applications. Clethodim is a potent acetyl-CoA A carboxylase (ACCase) inhibitor and herbicide. Clethodim inhibits ACCase in plants, thereby blocking fatty acid biosynthesis required for cell membrane and secondary metabolite production. Clethodim exhibits developmental toxicity and neurotoxicity in zebrafish embryos and larvae. Clethodim is used in studies on agricultural herbicides and developmental toxicity. | ||||||||||||||||||||
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References
- [1]. Xiong G, et al. Clethodim exposure induces developmental immunotoxicity and neurobehavioral dysfunction in zebrafish embryos. Fish & shellfish immunology. 2019 Mar;86:549-558. [Content Brief]
- [2]. WERLE R, et al. Distribution of Herbicide-Resistant Shattercane and Johnsongrass Populations in Sorghum Production Areas of Nebraska and Northern Kansas. Agronomy Journal, 2016, 108(1): 321-328.
- [3]. Santos KR, et al. Toxicogenetic, biochemical, and anatomical effects of the herbicide Clethodim on Allium cepa L. Environmental science and pollution research international. 2023 Dec;30(60):125388-125397.
- [4]. Siddiqui S, et al. Methomyl, imbraclaobrid and clethodim induced cytomixis and syncytes behaviors in PMCs of Pisum sativum L: Causes and outcomes. Saudi J Biol Sci. 2022 Sep;29(9):103390.
- [5]. Yanniccari M, et al. Inhibition of EPSPS overexpression of glyphosate-resistant Lolium perenne L. with a clethodim and glyphosate mixture. Pest management science. 2025 Jul;81(7):3516-3522.
- [6]. Wang H, et al. Clethodim exposure induced development toxicity and behaviour alteration in early stages of zebrafish life. Environmental pollution (Barking, Essex : 1987). 2019 Dec;255(Pt 1):113218. [Content Brief]