5-CITEP
5 CITEP is a potent HIV integrase inhibitor; its IC50s by multiple MIA and MPA are 2.3 ± 0.1 μM and 2.1 ± 0.1 μM, respectively.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 900779-63-7
- Formel: C12H8ClN5O2
- Molecular Weight:289.68
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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CAS. Nr. 900779-63-7
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Molecular Weight 289.68
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Formel C12H8ClN5O2
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SMILES
O=C(C=C(O)C1=NN=NN1)C2=CC=3C=C(Cl)C=CC3N2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Goldgur Y, et al. Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design. Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13040-3. [Content Brief]
[2]. Johnson AA, et al. Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop. J Biol Chem. 2006 Jan 6;281(1):461-7. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)