Alatrioprilat
Alatrioprilat is an orally active inhibitor of angiotensin-converting enzyme (ACE) (IC50=19.6 nM; Ki=9.8 nM) and enkephailnase (IC50=6.1 nM; Ki=5.1 nM). Alatrioprilat plays a key role in the metabolism of hormonal peptides through the degradation of nitric oxide and atrial natriuretic factor (ANF). Alatrioprilat can be used in the study of cardiovascular diseases.
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- CAS. Nr.: 135038-59-4
- Formel: C14H17NO5S
- Molecular Weight:311.35
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Chemical Information
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CAS. Nr. 135038-59-4
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Molecular Weight 311.35
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Formel C14H17NO5S
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SMILES
OC([C@H](C)NC([C@@H](CS)CC1=CC=C(OCO2)C2=C1)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Gros C, et al. Mixed inhibitors of angiotensin-converting enzyme (EC 3.4. 15.1) and enkephalinase (EC 3.4. 24.11): rational design, properties, and potential cardiovascular applications of glycopril and alatriopril[J]. Proceedings of the National Academy of Sciences, 1991, 88(10): 4210-4214. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Alatrioprilat Related Classifications
HY-117607 Related Classifications
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