Amphotericin X1
Amphotericin X1 is an 13-O-methyl derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, C.parapsilosis 937A, Cryptococcus neoformans 451, Aspergillus niger 57A and A.fumigatus with MIC values of 1 μg/mL, 8 μg/mL, 1 μg/mL, 2 μg/mL and 2 μg/mL, respectively.
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- CAS. Nr.: 136135-57-4
- Formel: C48H75NO17
- Molecular Weight:938.11
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
MIC: 1 μg/mL (Candida albicans 33/079), 8 μg/mL (C.parapsilosis 937A), 1 μg/mL (Cryptococcus neoformans 451), 2 μg/mL (Aspergillus niger 57A) and 2 μg/mL (A.fumigatus)[1]
Amphotericin X1 (compound 4) shows interesting antifungal activity combined with a pronounced reduction in haemolytic activity (EH50 of 42 μg/mL) against mammalianerythrocytes in vitro[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 136135-57-4
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Molecular Weight 938.11
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Formel C48H75NO17
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SMILES
CO[C@](C[C@@H]1O)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(O[C@H]([C@@H]([C@@H]2O)C)C)=O)O)O)O)O)O)O[C@](C[C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H]2C)O[C@@](O[C@@H]3C)([H])[C@H]([C@H]([C@@H]3O)N)O)([H])[C@@H]1C(O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Amphotericin X1 Related Classifications
HY-136153 Related Classifications
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