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Art. -Nr.: HY-155682

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Antibacterial agent 150

Antibacterial agent 150 (compound 5g) is an antibacterial agent with potent antibacterial activity against both Gram-positive bacteria and Gram-negative bacteria (MIC values ranging from 1-32 μg/mL). Antibacterial agent 150 can increase survival rate of MRSA (Methicillin-resistant Staphylococcus aureus)-infected mice.

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CAS. Nr.: 2766604-30-0
Formel: C₃₃H₄₅NO₆
Molecular Weight:551.71

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Antibacterial agent 150 Chemical Structure

CAS. Nr.: 2766604-30-0

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
A549	CC₅₀	>200 μM Compound: 5g	Cytotoxicity against human A549 cells incubated for 24 hrs by CCK8 assay Cytotoxicity against human A549 cells incubated for 24 hrs by CCK8 assay	[PMID: 37531743]
HEK293	CC₅₀	34.55 μM Compound: 5g	Cytotoxicity against HEK293 cells incubated for 24 hrs by CCK8 assay Cytotoxicity against HEK293 cells incubated for 24 hrs by CCK8 assay	[PMID: 37531743]
HepG2	CC₅₀	>200 μM Compound: 5g	Cytotoxicity against human HepG2 cells incubated for 24 hrs by CCK8 assay Cytotoxicity against human HepG2 cells incubated for 24 hrs by CCK8 assay	[PMID: 37531743]

Chemical Information

CAS. Nr. 2766604-30-0
Molecular Weight 551.71
Formel C₃₃H₄₅NO₆
SMILES

O=C1CC[C@@]2([C@H]([C@@H]([C@](C=C)(C[C@H]([C@@]3([C@@H](CC2)C)C)OC(COC(/C=C/C4=CC=C(C=C4)N(C)C)=O)=O)C)O)C)[C@@]13[H]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Min Li, et al. Design, synthesis, and evaluation of novel pleuromutilin aryl acrylate derivatives as promising broad-spectrum antibiotics especially for combatting multi-drug resistant gram-negative bacteria. Eur J Med Chem. 2023 Nov 5;259:115653. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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