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Art. -Nr.: HY-187235

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ClpP1P2-IN-1

ClpP1P2-IN-1 is a protease inhibitor targeting ClpP1P2 of Mycobacterium tuberculosis, with a K_i value of 0.04 μM. ClpP1P2-IN-1 inhibits the growth of Mycobacterium tuberculosis and shows low cytotoxicity against mammalian kidney cells. ClpP1P2-IN-1 can be used in the research of tuberculosis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 3069900-75-7
Formel: C₂₆H₂₇F₅N₄O₄S₂
Molecular Weight:618.64

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

ClpP1P2-IN-1 Chemical Structure

CAS. Nr.: 3069900-75-7

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

ClpP1P2-IN-1 (ClpP-1697) inhibits growth of Mycobacterium tuberculosis strain H37Rv with an average MIC of 0.11 μg/mL in Middlebrook 7H12 medium without catalase^[1].
ClpP1P2-IN-1 has no significant cytotoxicity against Vero green monkey kidney cells, with an IC₅₀ >20 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3069900-75-7
Molecular Weight 618.64
Formel C₂₆H₂₇F₅N₄O₄S₂
SMILES

FCC1=C(C2=NC=C(C(N[C@@H](CCC(O)C)C(N[C@@H](CCCC(F)(F)F)C(C3=NC=CS3)=O)=O)=O)S2)C=C(C=C1)F
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Nader Fotouhi, et al. Proteosome complex inhibitors targeting clpp1p2 protease. WO2025019626A2.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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