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Art. -Nr.: HY-124918

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Cremastranone

Cremastranone is an antiangiogenic homoisoflavone. Cremastranone can inhibit HUVECs cell proliferation, with a GI₅₀ value of 1.5 uM.

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CAS. Nr.: 107585-69-3
Formel: C₁₈H₁₈O₇
Molecular Weight:346.33

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Cremastranone Chemical Structure

CAS. Nr.: 107585-69-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cremastranone is an antiangiogenic homoisoflavone. Cremastranone can inhibit HUVECs cell proliferation, with a GI₅₀ value of 1.5 uM^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
HUVEC	GI₅₀	0.38 μM Compound: 1	Growth inhibition of human HUVEC cells assessed as reduction in cell number after 48 hrs by alamarBlue based fluorescence assay Growth inhibition of human HUVEC cells assessed as reduction in cell number after 48 hrs by alamarBlue based fluorescence assay	[PMID: 26035340]
Y79	GI₅₀	9.8 μM Compound: 1	Growth inhibition of human Y79 cells assessed as reduction in cell number after 48 hrs by alamarBlue based fluorescence assay Growth inhibition of human Y79 cells assessed as reduction in cell number after 48 hrs by alamarBlue based fluorescence assay	[PMID: 26035340]

Chemical Information

CAS. Nr. 107585-69-3
Molecular Weight 346.33
Formel C₁₈H₁₈O₇
SMILES

O=C1C2=C(C(OC)=C(C=C2OCC1CC3=CC=C(C(O)=C3)OC)O)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Lee B, et al. The first synthesis of the antiangiogenic homoisoflavanone, cremastranone. Org Biomol Chem. 2014 Oct 21;12(39):7673-7. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Cremastranone

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Biologische Aktivität

Chemical Information

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Calculators

Help & FAQs

Cremastranone Related Classifications

HY-124918 Related Classifications