Cyclomarin monomer-1
Based on 1 Customer Validation
Cyclomarin monomer-1 (Compound 5), a cyclomarin monomer, is a pre-dimerization precursor that can form Homo-BacPROTACs targeting the degradation of ClpC1. Cyclomarin monomer-1 binds to the Mtb ClpC1 protein with a KD of 3.5 nM. The MIC of Cyclomarin monomer-1 against the Mtb H37Rv standard strain is 1.6 μM. Cyclomarin monomer-1 can be used as a key intermediate in the development of Homo-BacPROTACs.
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- Reinheit : 97.77%
- Formel: C51H72N8O9
- Molecular Weight:941.17
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Speicherung:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
Chemical Information
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Appearance Solid
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Molecular Weight 941.17
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Formel C51H72N8O9
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Color White to off-white
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : ≥ 100 mg/mL (106.25 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (281 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0625 mL | 5.3125 mL | 10.6251 mL | 26.5627 mL |
| 5 mM | 0.2125 mL | 1.0625 mL | 2.1250 mL | 5.3125 mL | |
| 10 mM | 0.1063 mL | 0.5313 mL | 1.0625 mL | 2.6563 mL | |
| 15 mM | 0.0708 mL | 0.3542 mL | 0.7083 mL | 1.7708 mL | |
| 20 mM | 0.0531 mL | 0.2656 mL | 0.5313 mL | 1.3281 mL | |
| 25 mM | 0.0425 mL | 0.2125 mL | 0.4250 mL | 1.0625 mL | |
| 30 mM | 0.0354 mL | 0.1771 mL | 0.3542 mL | 0.8854 mL | |
| 40 mM | 0.0266 mL | 0.1328 mL | 0.2656 mL | 0.6641 mL | |
| 50 mM | 0.0213 mL | 0.1063 mL | 0.2125 mL | 0.5313 mL | |
| 60 mM | 0.0177 mL | 0.0885 mL | 0.1771 mL | 0.4427 mL | |
| 80 mM | 0.0133 mL | 0.0664 mL | 0.1328 mL | 0.3320 mL | |
| 100 mM | 0.0106 mL | 0.0531 mL | 0.1063 mL | 0.2656 mL |
Cyclomarin monomer-1 Related Classifications
HY-P11497 Related Classifications
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