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Art. -Nr.: HY-116389

ERG-IN-8

Name: ERG-IN-8
Brand: MedChemExpress
SKU: HY-116389
Availability: PreOrder

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

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Please store the product under the recommended conditions in the Certificate of Analysis.

CAS. Nr.: 926068-88-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	0.16 μM Compound: 14, AMTB	Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 mins before menthol challenge measured after 5 mins Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 mins before menthol challenge measured after 5 mins	[PMID: 20965726]
HEK293	IC₅₀	0.19 μM Compound: 14, AMTB	Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mins before icilin challenge measured after 5 mins Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mins before icilin challenge measured after 5 mins	[PMID: 20965726]
HEK293	IC₅₀	7.3 μM Compound: AMTB	Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium flux preincubated for 60 mins followed by menthol addition by Fluo-4 NW dye based fluorimetric method Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium flux preincubated for 60 mins followed by menthol addition by Fluo-4 NW dye based fluorimetric method	[PMID: 32787109]

CAS. Nr. 926068-88-4
Molecular Weight 394.53
Formel C₂₃H₂₆N₂O₂S
SMILES

O=C(C=1C=CC=CC1OCC=2C=CC=C(C2)C)N(CC=3SC=CC3)CCCN
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.