GPATCH2 - G-patch domain containing 2 Gene

Also Known as Pfa1; CT110; GPATC2; PPP1R30

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55105

About GPATCH2

Cytogenetic location: 1q41 Genomic coordinates (GRCh38): 1:217,426,992-217,631,090 (from NCBI)

This gene has 5 transcripts (splice variants), 205 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 2.6), thyroid (RPKM 1.9) and 25 other tissues.

Summary

The gene encodes a nuclear factor that may play a role in spermatogenesis and in tumor growth during breast Cancer. The encoded protein contains a G-patch domain with an RNA binding motif. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]

GPATCH2 Products (2)

mRNA Protein Name
NM_001297754.3 NP_001284683.1 G patch domain-containing protein 2 isoform 2
NM_018040.5 NP_060510.1 G patch domain-containing protein 2 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPATCH2 Protein Structure

G-patch

G-patch: G-patch domain (468 - 510)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 528 a.a.
Protein Preferred Names Protein Names

G patch domain-containing protein 2

  • cancer/testis antigen 110

Related Diseases

Diseases Alias
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS05619 GPATCH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus GPATCH2 VGNC VGNC:97449
Bos taurus GPATCH2 VGNC VGNC:29516
Macaca mulatta GPATCH2 VGNC VGNC:73009
Rattus norvegicus GPATCH2 RGD RGD:1308865
Canis familiaris GPATCH2 VGNC VGNC:41365
Mus musculus GPATCH2 MGD MGI:1915019
Others GPATCH2 NCBI