Inf2 - inverted formin, FH2 and WH2 domain containing Gene

Also Known as EG629699; 2610204M08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70435

Summary

Predicted to enable actin binding activity and small GTPase binding activity. Acts upstream of or within regulation of cellular component size. Predicted to be located in perinuclear region of cytoplasm. Is expressed in several structures, including adipose tissue; alimentary system; hemolymphoid system; nervous system; and reproductive system. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate E and focal segmental glomerulosclerosis 5. Orthologous to human INF2 (inverted formin 2). [provided by Alliance of Genome Resources, Apr 2022]

Inf2 Products (2)

mRNA Protein Name
NM_001374199.1 NP_001361128.1 inverted formin-2 isoform 2
NM_198411.2 NP_940803.2 inverted formin-2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
21278336 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within actin nucleation IDA
IDA: Inferred from direct assay
21278336 MGI
acts upstream of or within gene expression IDA
IDA: Inferred from direct assay
21278336 MGI
acts upstream of or within regulation of cellular component size IMP
IMP: Inferred from mutant phenotype
23349293 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inverted formin-2

  • formin, inverted

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS06806 INF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17887 Inf2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24356 Inf2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Inf2 NCBI NCBI:64423