IDO1-IN-37
IDO1/TDO-IN-13 (Compound 40) is a selective, non-competitive IDO1 inhibitor with an IC50 of 0.106 μM against IDO1. IDO1/TDO-IN-13 is applicable to the research of inflammatory diseases.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 3117126-69-6
- Formel: C13H6Cl2FNO2S
- Molecular Weight:330.16
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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IDO1 0.106 μM (IC50) |
IDO1/TDO-IN-13 (45 min) potently inhibits recombinant IDO1 with an IC50 of 0.106 μM; it also inhibits recombinant TDO2 with an IC50 of 6.91 μM[1].
IDO1/TDO-IN-13 (48 h) inhibits IDO1 activity in IFN-γ-stimulated BxPC-3 cells, with an IC50 of 5.09 μM[1].
IDO1/TDO-IN-13 (0-1.0 μM; 45 min) acts as a non-competitive inhibitor of recombinant IDO1 against D-tryptophan (HY-W012479)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 3117126-69-6
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Molecular Weight 330.16
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Formel C13H6Cl2FNO2S
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SMILES
ClC1=CC=C(C=C1)S(C2=NC3=C(O2)C=C(Cl)C(F)=C3)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
IDO1-IN-37 Related Classifications
HY-184028 Related Classifications
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