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Art. -Nr.: HY-170896

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iso-A11B5C1

Iso-A11B5C1 is an ionizable lipid that can be used in the synthesis of lipid nanoparticles (LNP). Iso-A11B5C1 is particularly suitable for muscle-specific mRNA delivery.

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CAS. Nr.: 3063868-70-9
Formel: C₄₁H₇₉N₃O₃
Molecular Weight:662.08

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

iso-A11B5C1 Chemical Structure

CAS. Nr.: 3063868-70-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
Chemical Information
Protokoll (1)
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Iso-A11B5C1 is an ionizable lipid that can be used in the synthesis of lipid nanoparticles (LNP). Iso-A11B5C1 is particularly suitable for muscle-specific mRNA delivery^[1].

In Vitro

iso-A11B5C1 LNP exhibits significant luciferase expression levels in HeLa cells after encapsulating Firefly Luciferase mRNA (HY-174790)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

In Vivo

iso-A11B5C1 LNP (i.m.) exhibits high mRNA expression in the muscle region and induces a strong humoral and cellular immune response in mice, suggesting its potential as an mRNA vaccine vector^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3063868-70-9
Molecular Weight 662.08
Formel C₄₁H₇₉N₃O₃
SMILES

CCCCCC(C)CCC(OCCCCCC(NCCN1CCCC1)C(NCCCCCCCC/C=C\CCCCCCCC)=O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Protokoll

All Molecular Biology

RNA extraction experimental
By lysing cells, releasing RNA, and removing impurities such as proteins and DNA, high-purity RNA products are finally obtained. The commonly used traditional method is the guanidine isothiocyanate/phenol/chloroform method (Trizol), which is suitable for a variety of animal materials including animal tissues, microorganisms, cultured cells, etc., and most plant materials.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Bowen Li, et al. Systems and methods for ai-based ionizable lipid development for lipid nanoparticle (lnp)-based cargo molecule delivery. WO2024234088.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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