Macrocarpal C
Based on 1 Customer Validation
Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation.
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- Reinheit: 95.0%
- CAS. Nr.: 142628-53-3
- Formel: C28H38O5
- Molecular Weight:454.60
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Speicherung:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biologische Aktivität
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
<10 μM
Compound: Macrocarpal C
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Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
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[PMID: 27142786] |
| HL-60 | IC50 |
<10 μM
Compound: Macrocarpal C
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Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay
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[PMID: 27142786] |
Chemical Information
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CAS. Nr. 142628-53-3
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Appearance Solid
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Molecular Weight 454.60
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Formel C28H38O5
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Color White to light yellow
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SMILES
CC(C)C[C@@H](C1=C(C(C=O)=C(C(C=O)=C1O)O)O)[C@@]2([C@@]3([H])[C@@]4([H])[C@](CCC([C@]3([H])CC2)=C)([H])C4(C)C)C
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Macrocarpal C Related Classifications
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