NOX5-IN-2
NOX5-IN-2 (Compound 17) is a selective NADPH oxidase 5 (NOX5) inhibitor with an IC50s of 0.70 μM. NOX5-IN-2 significantly inhibits NOX5-dependent production of ROS in freestyle293 cells (EC50: 1.8 μM). NOX5-IN-2 can be used for NOXs related diseases research, such as cardiovascular, cancer and neuroinflammation.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C18H11ClN6OS
- Molecular Weight:394.84
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
NOX5 0.70 μM (IC50) |
NOX1 >100 μM (IC50) |
NOX2 >100 μM (IC50) |
NOX4 >100 μM (IC50) |
DUOX1 >15 μM (IC50) |
Chemical Information
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Molecular Weight 394.84
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Formel C18H11ClN6OS
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SMILES
ClC1=CC=C2N=C(OC2=C1)SC3=C4C(N(N=N4)CC5=CC=CC=C5)=NC=N3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
NOX5-IN-2 Related Classifications
HY-174818 Related Classifications
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