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Art. -Nr.: HY-10867

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PF-622

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

PF-622 is a selective FAAH inhibitor, and can be used for study of analgesic and anxiolytic/antidepressant.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 898235-65-9
Formel: C₂₁H₂₂N₄O
Molecular Weight:346.43

Speicherung:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Data Sheet (264 KB)

PF-622 Chemical Structure

CAS. Nr.: 898235-65-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Publications (1)
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Bioz

Biologische Aktivität

Beschreibung

PF-622 is a selective FAAH inhibitor, and can be used for study of analgesic and anxiolytic/antidepressant^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	>25 μM Compound: PF-622	Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium level Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium level	[PMID: 19875281]
HEK293	IC₅₀	>10 μM Compound: PF-622	Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium level Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium level	[PMID: 19875281]

Chemical Information

CAS. Nr. 898235-65-9
Appearance Solid
Molecular Weight 346.43
Formel C₂₁H₂₂N₄O
SMILES

O=C(N1CCN(CC1)CC2=NC3=C(C=C2)C=CC=C3)NC4=CC=CC=C4
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Publications (1)

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Chin Med

Electroacupuncture to point Baihui confers anxiolytic effects by promoting oxytocin release from PVN in Mice. [Abstract]

2026 Jan 13;21(1):30. PMID: 41530867

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Ahn K, et al. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry. 2007;46(45):13019-13030. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

PF-622

1 Cited Publications

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PF-622

High-Throughput Bioactive Compound Library

Publications Citing Use of MedChemExpress (MCE) PF-622

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Chemical Information

Publications (1)

Reinheit & Dokumentation

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PF-622

High-Throughput Bioactive Compound Library

Publications Citing Use of MedChemExpress (MCE) PF-622

Biologische Aktivität

Chemical Information

Publications (1)

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PF-622 Related Classifications

HY-10867 Related Classifications