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Art. -Nr.: HY-N21614

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Phaeusmane F

Phaeusmane F is a eudesmane-type sesquiterpene that inhibits LPS (HY-D1056)-induced nitric oxide (NO) production in RAW 264.7 macrophages with an IC₅₀ of 4.8 μM. Phaeusmane F is found in the rhizomes of Curcuma phaeocaulis. Phaeusmane F can be used in research related to inflammatory responses.

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CAS. Nr.: 1450839-78-7
Formel: C₁₅H₂₀O₅
Molecular Weight:280.32

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Phaeusmane F Chemical Structure

CAS. Nr.: 1450839-78-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle NO Synthase Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC50	4.8 μM	Inhibition of lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages incubated for 24 h measured by Griess reagent assay with absorbance read at 540 nm. Inhibition of lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages incubated for 24 h measured by Griess reagent assay with absorbance read at 540 nm.	ejoc.201402465

In Vitro

Phaeusmane F (compound 6) (24 h; 1 μg/mL LPS stimulation) inhibits LPS-induced NO production in RAW 264.7 macrophages with an IC₅₀ of 4.8 μM, without exhibiting significant cytotoxicity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1450839-78-7
Molecular Weight 280.32
Formel C₁₅H₂₀O₅
SMILES

C[C@]12[C@@]([C@](O)(CCC2=O)C)([H])CC([C@](C1)(O3)O)=C(C)C3=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Liu Y, et al. Eudesmane-Type Sesquiterpenes from Curcuma phaeocaulis and Their Inhibitory Activities on Nitric Oxide Production in RAW 264.7 Cells. Eur J Org Chem. 2014:5540-5548.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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