Propargyl-C2-NHS ester
Based on 1 Customer Validation
Propargyl-C2-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- Reinheit: 97.0%
- CAS. Nr.: 906564-59-8
- Formel: C10H11NO4
- Molecular Weight:209.20
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Speicherung:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
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Help & FAQs
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Biologische Aktivität
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Non-cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 906564-59-8
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Appearance Solid-Liquid Mixture
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Molecular Weight 209.20
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Formel C10H11NO4
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Color Colorless to off-white
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SMILES
C#CCCCC(ON1C(CCC1=O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (478.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (243 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7801 mL | 23.9006 mL | 47.8011 mL | 119.5029 mL |
| 5 mM | 0.9560 mL | 4.7801 mL | 9.5602 mL | 23.9006 mL | |
| 10 mM | 0.4780 mL | 2.3901 mL | 4.7801 mL | 11.9503 mL | |
| 15 mM | 0.3187 mL | 1.5934 mL | 3.1867 mL | 7.9669 mL | |
| 20 mM | 0.2390 mL | 1.1950 mL | 2.3901 mL | 5.9751 mL | |
| 25 mM | 0.1912 mL | 0.9560 mL | 1.9120 mL | 4.7801 mL | |
| 30 mM | 0.1593 mL | 0.7967 mL | 1.5934 mL | 3.9834 mL | |
| 40 mM | 0.1195 mL | 0.5975 mL | 1.1950 mL | 2.9876 mL | |
| 50 mM | 0.0956 mL | 0.4780 mL | 0.9560 mL | 2.3901 mL | |
| 60 mM | 0.0797 mL | 0.3983 mL | 0.7967 mL | 1.9917 mL | |
| 80 mM | 0.0598 mL | 0.2988 mL | 0.5975 mL | 1.4938 mL | |
| 100 mM | 0.0478 mL | 0.2390 mL | 0.4780 mL | 1.1950 mL |
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