Antimalarial xanthones from Garcinia cowa

  • Planta Med. 1998 Feb;64(1):70-2. doi: 10.1055/s-2006-957370.
K Likhitwitayawuid ,  T Phadungcharoen ,  J Krungkrai
PMID: 9491769 DOI: 10.1055/s-2006-957370
Abstract

Five Xanthones from the bark of Garcinia cowa, namely 7-O-methylgarcinone E (1), cowanin (2), cowanol (3), cowaxanthone (4), and beta-mangostin (5), were found to possess in vitro antimalarial activity against Plasmodium falciparum with IC50 values ranging from 1.50 to 3.00 micrograms/ml. Complete 1H- and 13C-NMR assignments of these compounds are also reported.

Products