Ralpancizumab
Based on 1 Customer Validation
Ralpancizumab is a selective PCSK9 inhibitor with potential application in hemorrhagic stroke.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 96.23%
- CAS. Nr.: 1407495-04-8
- Molecular Weight:145.28 kDa
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Isotype
Human IgG2 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
PCSK9
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Human IgG2 kappa
Anwendung
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized PCSK9 Protein, Human (HEK293, C-His, HY-P70545A) can bind Ralpancizumab. The EC50 for this effect is 963.6 ng/mL. -
Flow Cytometry analysis of Hela cells labelling PCSK9 (red) with Ralpancizumab (anti-PCSK9) (HY-P99816). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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CAS. Nr. 1407495-04-8
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Appearance Liquid
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Molecular Weight 145.28 kDa
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Color Colorless to light yellow
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SMILES
[Ralpancizumab]
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Versand
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Data Sheet (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)