SCH 25393
SCH 25393 is a potent antibacterial agent.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 73212-54-1
- Formel: C12H14F3NO4S
- Molecular Weight:325.30
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
SCH 25393 shows antibacterial activity with MIC90 values of 6.25, 50, >100, >100, 25, 25, 25 mg/L for Staph. aureus, E. coli, Klebsiella spp., Enterobacter spp, Citrobacter spp., Proteus vulgaris, Proteus mirabilis, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS. Nr. 73212-54-1
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Molecular Weight 325.30
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Formel C12H14F3NO4S
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SMILES
FC(F)C(N[C@H](CF)[C@@H](C1=CC=C(C=C1)S(C)(=O)=O)O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Reinheit & Dokumentation
Verweise
[1]. Syriopoulou VP, et al. In vitro antibacterial activity of fluorinated analogs of chloramphenicol and thiamphenicol. Antimicrob Agents Chemother. 1981 Feb;19(2):294-7. [Content Brief]
[2]. Marca G, et al. In-vitro antibacterial activity of Sch 25393, a fluorinated analogue of thiamphenicol. J Antimicrob Chemother. 1984 May;13(5):423-7. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SCH 25393 Related Classifications
HY-115859 Related Classifications
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