Trabectedin derivative 2
Trabectedin derivative 2 (compound PL-12) is a trabectedin derivative that can be used in research on ovarian cancer, gastric cancer, and breast cancer.
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- CAS. Nr.: 3056692-81-7
- Formel: C39H41N5O8S
- Molecular Weight:739.84
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Trabectedin derivative 2 (Serial dilutions (9-point titration curve); 120 h) potently inhibits the viability of OV-90, NCI-N87, and MDA-MB-231 cells, with a CC50 of less than 10 nM for each cell line[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human ovarian papillary serous adenocarcinoma OV-90 cells, human gastric carcinoma NCI-N87 cells, human breast adenocarcinoma MDA-MB-231 cells
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Concentration:Serial dilutions (9-point titration curve)
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Incubation Time:120 h
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Result:Exhibited cytotoxic activity against OV-90, NCI-N87, and MDA-MB-231 cells, with a CC50 classification of +++ (CC50 < 10 nM) for all three cell lines.
Chemical Information
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CAS. Nr. 3056692-81-7
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Molecular Weight 739.84
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Formel C39H41N5O8S
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SMILES
N#C[C@@H]([C@]1([H])CC2=CC(C)=C3OC)N([C@](CO4)([H])C5=C(OCO6)C6=C7C)[C@@]([C@@](N1C)([H])C2=C3O)([H])[C@@](SC[C@](C8=CC=C9N)(NCCC8=C9)C4=O)([H])C5=C7OC(C)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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