country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-N12603

Copy Link Print Information

Typhatifolin B

Typhatifolin B (Compd 2), an anti-cancer agent, could remarkably induce cell apoptosis and G0/G1 cycle arrest, as well as block cell migration and invasion.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₃₄H₃₂O₅
Molecular Weight:520.61

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Typhatifolin B Chemical Structure

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Typhatifolin B (Compd 2), an anti-cancer agent, could remarkably induce cell apoptosis and G0/G1 cycle arrest, as well as block cell migration and invasion^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
4T1	IC₅₀	2.82 μM Compound: 2; TTB	Cytotoxicity against mouse 4T1 cells assessed as cell viability by MTT assay Cytotoxicity against mouse 4T1 cells assessed as cell viability by MTT assay	[PMID: 38387332]
A549	IC₅₀	3.21 μM Compound: 2; TTB	Cytotoxicity against human A549 cells assessed as cell viability by MTT assay Cytotoxicity against human A549 cells assessed as cell viability by MTT assay	[PMID: 38387332]
BEAS-2B	IC₅₀	5.27 μM Compound: 2; TTB	Cytotoxicity against human BEAS-2B cells assessed as cell viability by MTT assay Cytotoxicity against human BEAS-2B cells assessed as cell viability by MTT assay	[PMID: 38387332]
HeLa	IC₅₀	2.2 μM Compound: 2; TTB	Cytotoxicity against human HeLa cells assessed as cell viability by MTT assay Cytotoxicity against human HeLa cells assessed as cell viability by MTT assay	[PMID: 38387332]
HFF	IC₅₀	5.91 μM Compound: 2; TTB	Cytotoxicity against human HFF cells assessed as cell viability by MTT assay Cytotoxicity against human HFF cells assessed as cell viability by MTT assay	[PMID: 38387332]
MCF7	IC₅₀	8.64 μM Compound: 2; TTB	Cytotoxicity against human MCF7 cells assessed as cell viability by MTT assay Cytotoxicity against human MCF7 cells assessed as cell viability by MTT assay	[PMID: 38387332]
MDA-MB-231	IC₅₀	4.33 μM Compound: 2; TTB	Cytotoxicity against human MDA-MB-231 cells assessed as cell viability by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell viability by MTT assay	[PMID: 38387332]

In Vitro

Typhatifolin B (Compd 2) exhibits IC₅₀ values of 4.33 μM, 8.64 μM, 2.82 μM, 2.20 μM, 3.21 μM, 5.27 μM in MDA-MB231, MCF-7, 4T1, Hela, A549, BEAS-2B, HFF cells, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 520.61
Formel C₃₄H₃₂O₅
SMILES

O=C1C[C@@](OC2=C1C(O)=C([C@@](/C=C/C[C@@H](O)CCC3=CC=CC=C3)([H])C4=CC=CC=C4)C(O)=C2)([H])C5=CC=CC=C5
Structure Classification
- Flavonoids
- Flavonones
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Yu-Peng Li, et al. Rare flavanone-diarylheptanoid hybrids from Typha angustifolia shows anti breast cancer activity via activating TGF-β1/Smad signaling pathway. European Journal of Medicinal Chemistry. Volume 268, 15 March 2024, 116220.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen