UCL-1848 TFA
UCL-1848 TFA is a hSK1 blocker with an IC50 value of 1.1 nM. hSK1 is a small conductance calcium-activated potassium channel.
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- CAS. Nr.: 201147-53-7
- Formel: C32H34F6N4O4
- Molecular Weight:652.63
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
IC50: 1.1 nM (hSK1)[1]
Chemical Information
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CAS. Nr. 201147-53-7
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Molecular Weight 652.63
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Formel C32H34F6N4O4
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SMILES
O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F.C1(NCCCCCNC2=C3C=CC=CC3=[N+]4C=C2)=CC=[N+](CCCCC4)C5=CC=CC=C15
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Shah M, et al. The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines. Br J Pharmacol. 2000 Feb;129(4):627-30. [Content Brief]
[2]. Chen JQ, et al. bis-Quinolinium cyclophanes: 8,14-diaza-1,7(1, 4)-diquinolinacyclotetradecaphane (UCL 1848), a highly potent and selective, nonpeptidic blocker of the apamin-sensitive Ca(2+)-activated K(+) channel. J Med Chem. 2000 Sep 21;43(19):3478-81. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
UCL-1848 TFA Related Classifications
HY-122104 Related Classifications
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