18-Oxocortisol
Based on 1 Customer Validation
18-Oxocortisol is a derivative of cortisol that is produced by aldosterone synthase (CYP11B2). 18-Oxocortisol is a naturally occurring mineralocorticoid agonist. 18-Oxocortisol is a biomarker in adrenal vein sampling.
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- Pureté : 98.47%
- CAS No.: 2410-60-8
- Formule: C21H28O6
- Masse moléculaire:376.44
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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HY-147277
LorundrostatCYP11B2 Inhibitor -
HY-16276
OsilodrostatCYP11B1/CYP11B2 Inhibitor -
HY-B1438
CanrenoneEndogenous Metabolite -
HY-16276A
Osilodrostat phosphateCYP11B1/CYP11B2 Inhibitor -
HY-132827
OcedurenoneCorticosteroid Receptor Antagonist -
HY-B1438R
Canrenone (Standard) -
HY-132809
BaxdrostatAldosterone Synthase Inhibitor -
HY-B1472
Deoxycorticosterone acetateMineralocorticoid Receptor Agonist -
HY-113414
DeoxycorticosteroneMineralocorticoid Receptor Agonist -
HY-100471
EsaxerenoneMineralocorticoid Antagonist -
HY-B0251
EplerenoneAldosterone Blocker -
HY-16276R
Osilodrostat (Standard)CYP11B1/CYP11B2 Inhibitor
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Activité biologique
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2410-60-8
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Appearance Solid
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Masse moléculaire 376.44
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Formule C21H28O6
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Color White to off-white
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SMILES
O=C1CC[C@]2(C)[C@@]3([H])[C@@H](O)C[C@]4(C=O)[C@](C(CO)=O)(O)CC[C@@]4([H])[C@]3([H])CCC2=C1
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
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Fiche technique (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Nakamura Y, et al. 18-oxocortisol measurement in adrenal vein sampling as a biomarker for subclassifying primaryaldosteronism. J Clin Endocrinol Metab. 2011 Aug;96(8):E1272-8. [Content Brief]
[2]. Ulick S, et al. 18-oxocortisol, a naturally occurring mineralocorticoid agonist. Endocrinology. 1983 Dec;113(6):2320-2. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
18-Oxocortisol Related Classifications
HY-113151 Related Classifications
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